The horror film franchise 'Scream' is known for its iconic opening scene, which continues to define the series. The scene, featuring Drew Barrymore, blends classic horror elements with meta-commentary on the genre. It establishes the tone for the entire franchise and introduces the consistent whodunnit structure that the series is known for. The opening scene shocks audiences by killing off a major character early on, setting the precedent that no one is safe. It also references classic horror films and plays with genre tropes. The franchise has continued to offer meta-commentary and surprise audiences with twists and subversions, but the opening scene remains the defining trait of the series. It sets the stage for the sequels and serves as a bloody beacon that lights the way for the rest of the franchise [ecb165e7].